Ann Pharmacol Pharm | Volume 2, Issue 1 | Mini Review | Open Access
Munechika Enjoji1*, Motoyuki Kohjima2, Kenji Ohe1 and Kenshi Yao3
1Department of Clinical Pharmacology, Fukuoka University, Japan
2Departments of Hepatology and Pancreatology, Kyushu University Hospital, Japan
3Department of Endoscopy, Fukuoka University Chikushi Hospital, Japan
*Correspondance to: Munechika Enjoji
Fulltext PDFUnder the endoscopic observation with magnification endoscopy and narrow-band imaging, one of the novel findings in gastric neoplasms is white opaque substance (WOS), which is a manifestation of intracellular accumulation of lipid droplets. To elucidate the significance of this WOS formation, detailed lipid metabolism should be understood in gastric membranes. Recently, expression profiles of lipid-metabolism-associated genes in gastric tumor and non-tumor mucosa were investigated and reported. In this article, we explain the lipid accumulation and disturbance of lipid metabolism in gastric neoplasms.
Enjoji M, Kohjima M, Ohe K, Yao K. How and Why Do Lipid Droplets Accumulate in Gastric Epithelial Neoplasms? Ann Pharmacol Pharm. 2017; 2(1): 1016.