J Respir Med Lung Dis | Volume 2, Issue 3 | Research Article | Open Access
Navaneedha Krishnan S1 and Allwyn Vijay G2*
1Department of Pulmonology, Lotus Hospital, India
2Department of Thoracic Medicine, Government Villupuram Medical College, India
*Correspondance to: Allwyn Vijay G
Fulltext PDFIntroduction: Tuberculosis in India continues to remain a socioeconomic burden. The disease incidence and prevalence have considerably decreased in the recent times, due to the effective implementation of the national program. However, the smear negative tuberculosis continues to pose threat to the diagnostic and management of the clinicians. This study was done to evaluate the role of fiber optic bronchoscopy in detection of acid fast bacilli in smear negative tuberculosis.Methodology: A cross sectional study was done among 52 patients with smear negative tuberculosis visiting the tuberculosis center in Chennai. Bronchial wash and brush was done and samples were analyzed for AFB using Zeihl-Neelson technique, culture sensitivity using LJ medium and cytology. Line probe assay was also carried out among the study participants.Results: Bronchial wash showed 27% positivity by smear examination and 44% positivity by culture method. The study also revealed 2 patients with carcinoma by cytology. On comparison with line probe assay, fiber optic bronchoscopy showed statistical significant results of detection (p<0.05).Conclusion: Fiber optic bronchoscopy is an effective tool in detection of smear negative tuberculosis and will help in early diagnosis and prevention of secondary infections.
Bronchoscopy; Line probe assay; Smear negative tuberculosis
Navaneedha Krishnan S, Allwyn Vijay G. Role of Fiber Optic Bronchoscopy in Smear Negative Re-Treatment Pulmonary Tuberculosis. J Respir Med Lung Dis. 2017; 2(3): 1021.