World J Vasc Surg | Volume 3, Issue 1 | Review Article | Open Access

Carotid Paraganglioma Synchronous with another Ipsilateral Carotid Disease: A Systematic Literature Review

Francisco S Lozano-Sánchez1,4,5, Angel Muñoz2, José A de las Heras3, Carola Rubio Taboada1,4 and Maria Begoña García-Cenador1,5

1Department of Surgery, University of Salamanca, School of Medicine, Spain
2Service of Otorhinolaryngology, University of Salamanca, School of Medicine, Spain
3Service of Radiology, University of Salamanca, School of Medicine, Spain
4Service of Angiology and Vascular Surgery, University Hospital, Spain
5Salamanca Institute of Biomedical Research (IBSAL), Spain

*Correspondance to: María Begoña García Cenador 

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Carotid paragangliomas are infrequent tumors whose biology and natural history are unpredictable 
in a significant number of cases. Such infrequency and the different ways they manifest themselves 
pose a diagnostic/therapeutic challenge that is reflected in the final outcomes.
Seventy-five  percent  of  carotid  paragangliomas  adopt  simple  forms  (single  tumors  measuring 
<4  cm,  defined  and  resectable,  non-secretory  and  benign);  with  expert  treatment,  this  normal 
presentation  leads  to  excellent  results.  The  remaining  25%  are  complex  forms  (bilateral,  large, 
attached to the carotids, functional, malign, associated with other pathologies, etc); morbidity and 
mortality rates in these cases are clearly different. Within this complex group, there are a number of 
carotid pathologies (e.g., symptomatic stenosis or aneurysms) that are synchronous and ipsilateral 
to the paraganglioma.
This review sets out to address these situations in a unitary manner, with its references being very 
widely distributed in the literature, with the aim being to highlight their idiosyncrasies of diagnostic 
and  therapeutic  interest.  This  has  involved  a  systematic  literature  review  of  the  Medline  and 
Cochrane Library databases, up to 1 November 2019. This has located 12 articles with a total of 15 
Conclusion: Patients  with  these  exceptional  combinations  are  more  complex  and  constitute  a 
twin  challenge:  a)  diagnostic  (search  for  associations),  and  b)  therapeutic  (surgical  times  and 
prioritizations), with the aim being to avoid errors and achieve the best end results.




Lozano-Sánchez FS, Muñoz A, de las Heras JA, Taboada CR, GarcíaCenador MB. Carotid Paraganglioma Synchronous with another Ipsilateral Carotid Disease: A Systematic Literature Review. World J Vasc Surg. 2020;3(1):1020..

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