World J Psychiatry Ment Health Res | Volume 4, Issue 1 | Research Article | Open Access

Dopamine Receptor Binding in the Amygdala Interacts with Gender: A PET Study Using AMPT and [18F]fallypride

Patrizia Riccardi^1*, Xianming Carroll² and Larry Cahill³

Department of Psychiatry, Manhattan Psychiatric Center, MPC, USA
Department of Community Medicine, Mercer University, USA
Department of Neurobiology, University of California, Irvine, USA

^*Correspondance to: Patrizia Riccardi 

Fulltext PDF

Abstract

Dopaminergic neurotransmission plays an important role in many psychiatric disorders which show sex differences in incidence, clinical course, and treatment outcomes. We examined whether PET studies using [18F]fallypride performed prior to and following Alphamethylparatyrosine (AMPT) administration could be used to estimate sex differences in baseline Dopamine D2/D3 receptors (D₂D₃r) occupancy.

Keywords:

Dopamine; PET; Humans; [18F]fallypride; Alphamethylparatyrosine challenge

Citation:

Riccardi P, Carroll X, Cahill L. Dopamine Receptor Binding in the Amygdala Interacts with Gender: A PET Study Using AMPT and [18F]fallypride. World J Psychiatry Ment Health Res. 2020; 4(1): 1022..