World J Breast Cancer Res | Volume 5, Issue 1 | Research Article | Open Access
Mahani A*
Department of Radiation Oncology, Senior Resident, India
*Correspondance to: Anmol Mahani
Fulltext PDFBreast cancer is a globally prevalent malignancy, with an annual incidence of approximately 579,100 cases and causing around 270,000 deaths. In India, the Indian Council of Medical Research (ICMR) reports an annual diagnosis rate of 13.5% for Carcinoma Breast cases. Managing breast carcinoma involves surgery, radiotherapy, chemotherapy, endocrine therapy, or a combination of these interventions, influenced by various prognostic factors. Axillary surgery plays a pivotal role in breast cancer prognosis, with the American College of Surgeons Oncology Group (ACOSOG) Z0011 trial impacting surgical approaches. The After Mapping of the Axilla: Radiotherapy or Surgery (AMAROS) trial explored alternatives, revealing non-inferiority of axillary radiation with reduced morbidity. In modern radiotherapy, tangential beam breast radiotherapy offers enhanced target structure coverage, including axillary lymph nodes, while minimizing exposure to critical organs. This study assesses dose distribution and coverage of axillary lymph nodes (level I, II, and III) and organs at risk through tangential field breast/chest wall radiotherapy. Utilizing the Radiation Therapy Oncology Group (RTOG) guidelines and CT-based treatment planning, the study provides a comprehensive evaluation of clinical target volumes. The outcomes are discussed in the context of patient somatotype and radiotherapy techniques, emphasizing the potential benefits of tangential beam breast radiotherapy in optimizing treatment outcomes.
Mahani A. Is Tangential Beam Breast Radiotherapy Sufficient for Adequate Dosimetric Coverage of Axillary Lymph Node Level I, II and III in Indian Scenario? A Single Institutional Study. World J Breast Cancer Res. 2024; 5(1): 1024..