Neurol Disord Stroke Int | Volume 1, Issue 1 | Research Article | Open Access

Positive Slow Wave of P3b is Significantly Enhanced in Post TGA Subjects

Shugo Suwazono1, Kwee IL1,2 and Tsutomu Nakada1,2*

1Center for Integrated Human Brain Science, Brain Research Institute,University of Niigata, Japan
2Department of Neurology, University of California Davis, USA

*Correspondance to: Tsutomu Nakada 

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Abstract

Modern imaging studies have shown that Transient Global Amnesia (TGA) is associated with structural changes in the hippocampus. We investigated the Slow Wave (SW) component following P3b of visual Event Related Potentials (ERP) in nine post TGA subjects and sixteen age-matched controlsin attempt ofidentifying objective electrophysiological evidence of changes in memory processing in TGA subjects. While P3b was comparable in both groups, SW in TGA subjects was significantly enhanced in the frontal regions. The findings strongly the concept that SW enhancement reflects frontal hyperactivity in high load conditions, and represent an objective sign that clinical recovery of TGA likely reflects neural reorganization.

Citation:

Suwazono S, Kwee IL, Nakada T. Positive Slow Wave of P3b is Significantly Enhanced in Post TGA Subjects. Neurol Disord Stroke Int. 2018; 1(1): 1002.

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