J Plast Surg | Volume 3, Issue 1 | Research Article | Open Access
Saad HA1*, Baz A2, Eraky ME1, El-Taher AK1, Riad M1, Farid MI1 and Sharaf K1
1Department of Surgical, Zagazig University Hospital, Zagazig city, Sharkia, Egypt 2Department of Surgical, Alahrar Tteaching Hospital, Zagazig city, Sharkia, Egypt
*Correspondance to: Hassan A Saad
Fulltext PDFAim: The purpose of this study was to look into any correlations between muscle and adipose features and the severity and prognosis of patients hospitalized with Acute Pancreatitis (AP). Methods: In total, 392 hospitalized patients and 309 controls were enrolled in the study analysis between May 2017, and January 1st, 2022. A computed tomography scan was used for each population to evaluate muscle and adipose parameters. The influence of variables on the development of either Moderately Severe Acute Pancreatitis (MSAP) or Severe Acute Pancreatitis (SAP) was evaluated using univariate and multivariate logistic regression analysis. Cox regression analysis was used to look at the relationships between disease recurrence and death. Results: The controls had lower levels of Skeletal Muscle Attenuation (SMA) and visceral and subcutaneous adipose tissue attenuation (both p<0.05). The AP patients, on the other hand, had higher visceral and subcutaneous adipose tissue (144.25 vs. 97.81 cm2, p<0.001). Visceral Adipose Tissue (VAT) and SMA showed a significant difference in the AP severity groups, with p-values of 0.014 and 0.003, respectively. When looking at many factors at once, VAT and SMA were linked to either SAP or MSAP (95% CI 0.953-0.993, p=0.010) or 1.000-1.006, p=0.041, with odds ratios of 1.003 and 0.973, respectively. Low SMA was linked to a higher death rate in MSAP and SAP patients, according to Cox regression analysis (HR: 10.500, 95% CI 1.344-82.025, p=0.025). There was also a link between a lower risk of acute pancreatitis happening again in one year and a VAT loss of more than 17% (HR: 0.427, 95% CI 0.189-0.967, p=0.041). Conclusion: SMA and VAT significantly impacted the severity and prognosis of AP patients. Patients should maintain a good diet and exercise routine after being released from their VAT and gaining muscle. Their prognosis will improve as a result.
Skeletal muscle; Subcutaneous adipose tissue; Recurrent acute pancreatitis; VAT; SMA
Saad HA, Baz A, Eraky ME, El-Taher AK, Riad M, Farid M, et al. Visceral Abdominal Fat and Muscle Mass Impact on Patients with Severe Acute Pancreatitis' Risk for Death. J Plast Surg. 2023; 3(1): 1015.