J Neurol Neurosurg Spine | Volume 4, Issue 1 | Review Article | Open Access

The Study of Genetic Mutations in Gene IKBKG in BlochSiemens Syndrome

Shahin Asadi*, Samira Sattari, Mahsa Jamali, Soheil Nemati Arzeloo and Mona Habashizadeh

Department of Medical Genetics and Molecular Research, Tabriz University of Medical Sciences, Iran

*Correspondance to: Shahin Asadi 

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The Bloch-Siemens syndrome is a genetic dermatological disorder affecting the skin, hair, teeth, and central nervous system. Progressive skin changes occur in four stages, the first of which appear in early infancy or can be present at birth. This syndrome is an X-linked dominant genetic disorder caused by mutations in the IKBKG gene.


Bloch-Siemens syndrome; Genetic dermatological disorder; Mutations in the IKBKG gene


Asadi S, Sattari S, Jamali M, Nemati Arzeloo S, Habashizadeh M. The Study of Genetic Mutations in Gene IKBKG in Bloch-Siemens Syndrome. J Clin Neurol Neurosurg Spine. 2019; 4(1): 1015.

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