J Gastroenterol Hepatol Endosc | Volume 2, Issue 4 | Research Article | Open Access
Barnhill MS1*, Morales SJ1, Albugeaey M2, AlJaser W2, Chalhoub W2, Holmes M3, Zeck J3 and Haddad N2
1Department of Internal Medicine, MedStar Georgetown University Hospital, USA
2Division of Gastroenterology, MedStar Georgetown University Hospital, USA
3Department of Pathology, MedStar Georgetown University Hospital, USA
*Correspondance to: Michele Barnhill
Fulltext PDFBackground: Solid pancreatic masses require sampling before a diagnosis can be made. Historically, diagnostic accuracy rates vary between 78% and 95% with fine needle aspiration (FNA). The Acquire needle (Boston Scientific) is a newly manufactured endoscopic ultrasound (EUS) fine needle biopsy (FNB) device created to increase diagnostic yield. The aim of this study was to compare diagnostic yield of the Acquire needle to our institution’s standard EUS sampling needles.
Methods: This is a retrospective study of patients who underwent EUS tissue acquisition (EUSTA) for solid pancreatic masses using our 22G standard needles (n=58) and the 22G novel needle (n=23). The primary outcome was overall diagnostic yield. The secondary outcome was diagnostic rate based on location of the pancreatic lesion.
Results: Nineteen of the 23 (83%) pancreatic masses biopsied using the novel needle device were diagnostic, compared with 32 of 58 (55%) biopsied using the control needles (p=0.0237). Diagnostic rates specific to the lesions in the pancreatic head were 75% (n=12) in the Acquire group and 53% (n=20) in the control group (p=0.1452). Diagnostic rates specific to the lesions in the pancreatic body were 100% (n=7) in the Acquire group and 60% (n=12) in the control group (p=0.0681). Conclusions: The Acquire is a novel EUS fine needle biopsy device that provides excellent diagnostic accuracy, demonstrating a statistically significant increase in overall diagnostic rate when directly compared to our institution’s standard tissue acquisition needles (ProCore and Expect). To our knowledge, this is the first ever study to directly compare the diagnostic yield of the Acquire needle with biopsy needles used in current standard practice.
Endoscopic ultrasound; Fine needle biopsy device; Pancreatic
Barnhill MS, Morales SJ, Albugeaey M, AlJaser W, Chalhoub W, Holmes M, et al. A Single Center’s Experience with the Novel Acquire Endoscopic Ultrasound Fine Needle Biopsy Device. J Gastroenterol Hepatol Endosc. 2017;2(4):1021.