J Gastroenterol Hepatol Endosc | Volume 5, Issue 2 | Case Report | Open Access

Recurrence of Helicobacter pylori Infection after Successful Eradication Therapy in Egyptian Patients

Mohamed AA Bassiony*, Amr T El Hawary and Marwan N Elgohary

Department of Internal Medicine, Gastroenterology & Hepatology Unit, Zagazig Faculty of Medicine, Egypt

*Correspondance to: Mohamed AA Bassiony* 

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Background: Helicobacter pylori(H. pylori), a highly prevalent gastrointestinal organism, infects more than 50% of the global population. It is the most common risk factor for peptic ulcer disease, cancer stomach & gastric lymphoma. Eradication  therapy  regimens  for H.  pylori are  highly  effective.  However,  bacterial  resistance to  antibiotics  &  patients  non-adherence  to  the  treatment  regimens  significantly  increased  the recurrence rates of H. pylori infection in the last few decades. Study  Aim: To  assess  the  prevalence  &  possible  risk  factors  of H.  pylori recurrence  in  Egyptian patients after eradication therapy. Patients  and  Methods: We  evaluated  &  followed  up  157  patients  for  one  year  after  confirmed successful eradication of H. pylori infection. We investigated the patients at 3, 6, 9 & 12 months for recurrence of H. pyloriinfection using urea breathe & stool antigen tests. Results and Conclusion:We found a one-year recurrence rate of 19% after successful eradication therapy  of H.  pylori.  The  education  level  of  the  patients  &  alcohol  consumption  were  the  most significant predictors of H. pylori recurrence. The one-year recurrence rate in our study is high but comparable to those reported in the developing countries most probably due to high rates of reinfection & non-adherence to the preventive measures.


H. pylori; Proton pump inhibitors; Eradication therapy; Bacteria resistance; Recurrence


Bassiony MAA, El Hawary AT, Elgohary MN. Recurrence of Helicobacter pylori Infection after Successful Eradication Therapy in Egyptian Patients. J Gastroenterol Hepatol Endosc. 2020;5(3):1085..

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