J Gastroenterol Hepatol Endosc | Volume 4, Issue 2 | Case Report | Open Access

Esomeprazole Induced Liver Injury

Santosh Raj Sharma*, Dhuha Alhankawi and James Park

Department of Hepatology, New York University, USA

*Correspondance to: Santosh Raj Sharma 

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Proton Pump Inhibitors (PPIs) are one of the most widely prescribed medications. Recently PPIs have been linked to causing dementia, vitamin B12 deficiency, Clostridium difficile, interstitial nephritis, osteopenia etc. We present a case of a 65 years old female who developed biopsy proven Acute Liver Failure (ALF) after starting Esomeprazole a PPI. The liver recovered after Esomeprazole was stopped. Our case provides convincing evidence that Esomeprazole could be linked to liver injury. Once thought the safest and the most prescribed group of medications, is it time to add one more adverse effect on their extensive list of adverse effects?


Sharma SR, Alhankawi D, Park J. Esomeprazole Induced Liver Injury. J Gastroenterol Hepatol Endosc. 2019;4(2):1056.

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