J Gastroenterol Hepatol Endosc | Volume 3, Issue 2 | Research Article | Open Access
Hüseyin Şimşek1, Ozlem Tezol1*, Arzu Gülseren2, Didem Derici Yıldırım3, Arzu Kanık3 and Yusuf Usta2
1Department of Pediatrics, Mersin University, Turkey
2Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Mersin University, Turkey
3Department of Biostatistics, Mersin University, Turkey
*Correspondance to: Ozlem Tezol
Fulltext PDFBackground: Data on the prevalence of ulcers in children are insufficient. We aimed to investigate the frequency of peptic ulcer and evaluate the effects of H. pylori infection, gender, age on peptic ulcer, and the value of endoscopy in children.
Methods: Eight hundred patients with chronic abdominal pain were enrolled. Upper endoscopy was performed if all the initial evaluations were normal. Clinical findings, laboratory results, endoscopic and pathologic findings were investigated retrospectively.
Results: Among all patients with chronic abdominal pain, ulcer disease was identified in 84 (10.5%) patients. Ulcer was observed 1.7 times more frequently in patients with H. pylori positivity. There is a significant relationship between H. pylori infection and the ulcer frequency (p=0.03). There was a non significant relationship between H. pylori infection and ulcer types as duodenal or gastric ulcer (p=0.08). There was no statistical relationship between ulcer and sex (p=0.45). We determined no statistical relationship between the ulcer types and sex (p=0.68). Age had an impact on ulceration, age was a good indicator for the discrimination of patients with or without ulcer (p=0.010). Each one-year increase of age caused a 1.1 fold increase in ulceration. The results revealed that age, sex and H. pylori positivity were not risk factors for gastric ulcer Conclusions: Ulcer disease is one of organic causes of chronic abdominal pain in children. Endoscopy is an important procedure for the diagnosis. However, more studies are needed to determine the causes and accurate prevalence of the ulcer.
Chronic abdominal pain; Children; Endoscopy; Ulcer disease
Şimşek H, Tezol O, Gülseren A, Yıldırım DD, Kanık A, Usta Y. Peptic Ulcer Disease in Children with Chronic Abdominal Pain. J Gastroenterol Hepatol Endosc. 2018;3(2):1043.