Betti TER1 , Spolidório RD1 , Dias FJN2 , Ferreira CRL1 , Pino DS2 and Pinto SAA2 *
1 School of Dentistry, Herminio Ometto University Center, Brazil 2 School of Medicine and Dentistry, São Leopoldo Mandic, BrazilFulltext PDF
PRF (Platelet-Rich Fibrin) is a by-product of obtaining Platelet-Rich Plasma (PRP). Both are widely used in the medical and dental fields, being used mainly as adjuvant therapy in regenerative procedures. In dentistry, PRP is widely used in maxillofacial surgeries. PRF is widely used in bone grafting for dental implants and soft tissue grafts, such as connective tissue grafts, and recently it has also gained prominence in the area of orofacial harmonization. PRP and PRF are concentrates that contain growth factors such as Transforming Growth Factor Beta (TGF-β), Insulin-like Growth Factor type 1 (IGF 1), Platelet-Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF), Fibroblast Growth (FGF), Epidermal Growth Factor (EGF) and Platelet-Derived Epidermal Growth Factor (PDEGF), with important utility in the medical-aesthetic area, accelerating tissue repair results. In cases of facial rejuvenation surgery and resurfacing and also in percutaneous collagen stimulation procedures, the use of these concentrates improves the ageing aspect of the face, smoothing expression lines and improving volume and skin texture. Thus, this work seeks to elucidate the results found in the literature regarding the use of concentrates such as PRP and PRF, making a comparison of clinical use found in published scientific papers.
Ageing; Growth Factors; Platelet-rich plasma
Betti TER, Spolidório RD, Dias FJN, Ferreira CRL, Pino DS, Pinto SAA. The Use of Platelet-Rich Plasma and Platelet-Rich Fibrin in Dentistry and Orofacial Harmonization: A Literature Overview. J Dent Oral Biol. 2023; 8(1): 1205. ISSN: 2475-5680.