J Dent Oral Biol | Volume 5, Issue 2 | Review Article | Open Access

The Use of Antibiotics vs. Probiotics in Periodontitis Therapy

Nada Tawfig Hashim

Department of Dentistry, University of Khartoum, Sudan

*Correspondance to: Nada Tawfig Hashim 

Fulltext PDF


Periodontal disease is an inflammatory disease, provoked in response to periodontopathogens in the biofilm of the subgingival plaque, affecting tissues supporting the teeth. Members of the red complex, such as Porphyromonas gingivalis and Tannerella forsythia are considered as the most pathogenic microbial components at present. Likewise, Aggregatibacter actinomycetemcomitans is associated with periodontal disease, but it does not belong to the red complex. The gold standard in periodontal treatment is scaling and root planning. Systemic antibiotic therapy is indicated to control deep periodontal pockets with microbial invasion at epithelial level that are difficult to access with disease progressing overtime. Resistance of bacterial species to antibacterial treatment has been considered as a global problem following the excessive use of these drugs. In recent years, the use of probiotics which display a strong inhibitory effect against certain periodontal pathogens has become more prevalent. Thus, this review deliberates the adjunctive use of antibiotics versus probiotics in periodontitis therapy.


Periodontitis; Antibiotics; Probiotics; Biofilm; Root planning


Hashim NT. The Use of Antibiotics vs. Probiotics in Periodontitis Therapy. J Dent Oral Biol. 2020; 5(2): 1166. ISSN: 2475-5680.

Subscribe to Our Newsletter