J Dent Oral Biol | Volume 2, Issue 1 | Case Report | Open Access

The Progress of TSP-1 in the Research of Various Kinds of Related Tumors

Xue-qin ZHOU2, Sen YANG1,2*, Li-juan GUO1, Xiu-fa TANG3 and Xiao-yi WANG3

1Suining Central Hospital, China
2Zunyi Medical University, China
3West China College of Stomatology, Sichuan University, China

*Correspondance to: Yang Sen 

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Thrombospondin 1 (TSP-1) as a kind of inhibiting angiogenesis important substances, widely distributed in human tissues, but also makes it occupy the irreplaceable position in the formation of different tissues of tumor, growth, differentiation, metastasis, currently available in the literature about TSP-1 in various types of cancer (such as prostate cancer, bladder cancer, non-small cell lung cancer, breast cancer, cervical cancer, pancreatic cancer, etc.) the occurrence and development of the role of the reported It is often seen. It undoubtedly provides new directions and guidelines for medical science research workers in the field of cancer and its relationship with tumor would has irreplaceable role for prognosis and exploration the clinical tumor’s etiology, diagnosis and treatment. This review is a summary of the discovery and development of TSP-1 in various types of tumor research.


Thrombospondin 1 (TSP-1); CD47; Solid tumors; Blood system malignant tumor


Xue-qin ZHOU, Sen YANG, Li-juan GUO, Xiu-fa TANG, Xiao-yi WANG. The Progress of TSP-1 in the Research of Various Kinds of Related Tumors. J Dent Oral Biol. 2017; 2(1): 1021.

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