Reena Y1, Kanika C1, Aditi G1*, Shilpi A2 and Rakesh K2
1Department of Obstetrics & Gynecology, Lady Hardinge Medical College, India 2Department of Pathology, Lady Hardinge Medical College, IndiaFulltext PDF
Background: Xanthogranulomatous inflammation is an unusual type of chronic inflammation which causes tissue destruction by inflammatory cells mainly foamy histiocytes. Such inflammation of the female genital tract is rare and limited to the endometrium. Only few cases of xanthogranulomatous inflammation of genital tract have been reported so far in literature. Case Report: A 32-year-old nulliparous female presented with chief complaints of heavy menstrual bleeding and severe dysmenorrhea for eight years with failed medical management. Per-abdominal examination revealed a suprapubic firm, tender mass of around 14 weeks gravid uterus size. On per vaginal examination, uterus was retroverted with a tender, solid-cystic mass in the right adnexa extending till pouch of Douglas with restricted mobility. Her CA125 (510 U/ml) were raised. Pelvic ultrasound demonstrated adenomyotic uterus and endometriotic cysts in right adnexa with moderate right hydroureteronephrosis which was confirmed on CT urography. She underwent cystoscopic DJ stenting followed by total abdominal hysterectomy with right salpingooophorectomy and left salpingectomy. DJ stents were removed on day 7. The postoperative period was uneventful. Histopathological examination of the sent specimen revealed xanthogranulomatous salpingo-oophoritis of right fallopian tube and ovary with endometriotic features and adenomyotic uterus with secretory endometrium. Conclusion: Xanthogranulomatous inflammation of the tubes and ovaries clinically, radiologically and grossly may mimic ovarian malignancy. Thus, a preoperative diagnosis can prevent radical surgical treatment.
Reena Y, Kanika C, Aditi G, Shilpi A, Rakesh K. Xanthogranulomatous Salpingo-Oophoritis – A Rare Case Report. J Clin Obstet Gynecol Infertil. 2024; 8(1): 1063..