J Clin Nephrol Kidney Dis | Volume 3, Issue 1 | Case Report | Open Access

Granulomatous Interstitial Nephritis as the Presentation of Systemic Sarcoidosis

Rollino Cristiana*, Ferro Michela, Beltrame Giulietta, Quattrocchio Giacomo and Roccatello Dario

Department of Nephrology and Dialysis, Ospedale San Giovanni Bosco, Turin, Italy

*Correspondance to: Cristiana Rollino 

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Sarcoidosis is a systemic disease rarely presenting with isolated renal involvement. In about a quarter of cases interstitial granulomatous nephritis develops, which can only be detected by a renal biopsy.
We present the case of a woman who came to our observation because of moderate renal failure with slight urine abnormalities (proteinuria 0.3 g/day, few hyalo-granular casts in the urinary sediment) and no systemic symptoms. Renal biopsy showed giant cell granulomas and infiltration of the renal interstitium by small lymphocytes and plasma cells. The following examinations allowed us to diagnose renal and extrarenal sarcoidosis.


Cristiana R, Michela F, Giulietta B, Giacomo Q, Dario R. Granulomatous Interstitial Nephritis as the Presentation of Systemic Sarcoidosis. J Clin Nephrol Kidney Dis. 2018; 3(1): 1016.

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