Int J Family Med Prim Care | Volume 3, Issue 2 | Research Article | Open Access

Therapeutic Implications of Genetic Risk Stratification for CAD Cognitive Performance of Healthy Older Adults is Resistance to Moist Heat Exposure: Results of a Controlled Trial

Leopold Busse A1 *, Rodrigues Guedes M1 , Maria Trezza B1 , Paulo Nascimento Saldiva H3 , Wilson Jacob-Filho W1 and Teixeira Gonçalves F2

1 Department of Internal Medicine, University of São Paulo Medical School, Brazil 2 Institute of Astronomy, Geophysics, and Atmospheric Sciences, University of São Paulo Medical School, Brazil 3 Department of Pathology, University of São Paulo Medical School, Brazil

*Correspondance to: Leopold Busse A 

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Abstract

Ageing leads to changes in temperature control mechanisms that make elderly people more vulnerable to temperatures out of their comfort range. In addition to diminished thermoregulatory mechanisms, normal ageing is associated with cognitive decline. To compare the effects of moist heat and dry heat in controlled environment on the cognitive performance among community-dwelling older persons, we carried out a controlled trial. Fifty-one healthy older adults from outpatient geriatrics clinic participated in two sets of cognition tests in two environmental conditions, one with dry heat of 32.5°C and 30% Relative Humidity (RH), and one with a humid heat of 32.5°C and 70% RH. Five tests of the Automated Neuropsychological Test Battery of Cambridge (CANTAB) were applied in order to evaluate executive function, processing speed and attention. The mean age was 73.27 years, 72.55% were female, with a mean educational level of 11.58 years. No significant difference was found in the global cognitive score between dry heat and moist heat (100.47 ± 8.91, 99.52 ± 7.57, p=0.4). In our sample of healthy physically active older adults there were no changes in cognitive performance when exposed to moist heat stress compared to dry heat.

Keywords:

Aging; Cognition; Neuropsychological tests; Moist heat exposure

Citation:

Leopold Busse A, Rodrigues Guedes M, Maria Trezza B, Paulo Nascimento Saldiva H, Wilson Jacob-Filho W, Teixeira Gonçalves F. Therapeutic Implications of Genetic Risk Stratification for CAD Cognitive Performance of Healthy Older Adults is Resistance to Moist Heat Exposure: Results of a Controlled Trial. Int J Fam Med Prim Care. 2022; 3(2): 1060..

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