Maya Datt Joshi
1Department of Biomedical and Bioinformatics Engineering, Shobhit Institute of Engineering and Technology
(Deemed to be University), India
2Department of Biotechnology, Shobhit Institute of Engineering and Technology (Deemed to be University), India
The large increase in number of coronaviruses has been found and also coronavirus genomes has been sequenced and found that the given an abnormal event to perform genomics studies and bioinformatics studies on the family of viruses. This coronavirus has large genome (26.4 kb to 31.7 kb) compare with among other RNA viruses. Coronavirus has large amount of G+C contents vary from 32% to 43%. Phylogenetically coronaviruses has 3 genera lineages namely as Alpha coronavirus, Beta coronavirus and Gamma coronavirus. So Beta coronavirus has again divided into 4 subdivisions namely as A, B, C and D. Coronaviruses are well established pathogens of animals and humans. Variable number of small amount of ORF presents between the conserved genes and also present in posterior of nucleocapsid gene. According to these applications of Bioinformatics studies has been involved to prevent the COVID-19. There is large amount of Bioinformatics NGS studies is going on for COVID-19 studies. Using Bioinformatics tools and software's we can predict the protein structure and also identify which genes are responsible for causing coronavirus.
Covid-19; Covid; Corona Virus; Coronavirus disease 2019
Ravi Teja KS, Joshi MD. Applications of Bioinformatics Tools for Prevention COVID-19 Infection. Int J Fam Med Prim Care. 2021; 2(2):1034.