Ann Short Rep | Volume 2, Issue 2 | Research Article | Open Access
Khalid S Aljabri*
Department of Endocrinology, King Fahad Armed Forces Hospital, Saudi Arabia
*Correspondance to: Khalid S Aljabri
Fulltext PDFIntroduction: Vitamin D deficiency and Type 2 Diabetes Mellitus (T2DM) remain major health problems. Few published researches have been found that surveyed the prevalence of VDD in patients with T2DM in Saudi Arabia. We conducted a cross sectional study to investigate the prevalence vitamin D deficiency in male patients with T2DM.
Method: A cross-sectional single centre study was conducted in 1145 patients with T2DM. Patients with T2DM attending the Diabetes centre at King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia between January 2018 and December 2018. The serum concentration of 25(OH)D and HbA1c were measured.
Results: There were 1145 male patients with T2DM. The mean age was 54.4 ± 16.5 years. The mean and median 25(OH)D concentrations were 52.7 ± 27.2 and 46.6 respectively.The prevalence of different vitamin D status were; 55.6% deficient, 27.3% insufficient and 17.0% sufficient. VDD patients were statistically significant younger than patients with vitamin insufficiency or sufficiency (52.5 ± 16.4 vs. 56.3 ± 17.0 vs. 57.2 ± 15.2 respectively, p<0.0001). Vitamin D deficient patients have statistically significant higher HbA1c than patients with vitamin insufficiency or sufficiency (8.3 ± 2.0 vs. 7.7 ± 1.7 vs. 7.4 ± 1.7 respectively, p<0.0001). Moreover, vitamin D deficient patients have statistically significant lower 25(OH)D than patients with vitamin insufficiency or sufficiency (34.3 ± 8.9 vs. 60.6 ± 7.2 vs. 100.3 ± 23.0 respectively, p<0.0001).The mean 25(OH)D was upward as age advanced with highest frequency of VDD was found in the sixth decades. In addition, 25(OH)D concentration was significantly positively correlated with age (r=0.128, p<0.0001) and significantly negatively correlated with HbA1c (r= -0.179, p<0.0001). HbA1c ≥7 was significantly associated with higher VDD.Regression analysis of odd ratio of risk factors for patients with VDD showed that age and HbA1c were statistically significant associated with VDD, (OR=0.979; 95% CI=0.979-0.988), p<0.0001) and (OR=1.263; 95% CI=1.167-1.367, p<0.0001) respectively.
Conclusion: The prevalence of VDD in male patients with T2DM is high.
Type 2 diabetes mellitus; Vitamin D deficiency; 25(OH)D
Aljabri KS. Vitamin D Deficiency in Saudi Men with Type 2 Diabetes Mellitus. Ann Short Reports. 2019;2:1037.