Ann Short Rep | Volume 3, Issue 2 | Research Article | Open Access

“Screening of Cervical Cancer Acts as New Insights” - For Early Detection and Prevention by a Modern OncoE6 Protein Detection Assay

Sahida Abedin*

Department of Virology, Mymensingh Medical College, Bangladesh

*Correspondance to: Sahida Abedin 

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Abstract

Cervical cancer is the most burning issue for women worldwide. It is the fourth leading type of cancer in women and increasing day by day. Persistent Infection with high-risk Human papillomavirus (HPV) is the main cause for the progression of cervical precancerous and cancerous lesion. The oncoproteins of HPV mainly E6 and E7 are responsible for the neoplastic alteration in epithelial tissues. The Objective of the study was screening of cervical precancerous and cancerous lesion of the patient attending at Mymensingh Medical College, Hospital. Following universal safety precautions, a total of 280 endocervical swabs were collected from VIA outdoor and Colposcopy Clinic of Obstetrics and Gynecology Department of MMCH between April 2016 to March 2017. In this study VIA, nested PCR and OncoE6 cervical test were done on 280 cases. A total of 24 (8.5%) cases were positive for HPV DNA by nested PCR and 21 (7.5%) cases were positive for OncoE6 protein by OncoE6 cervical test. On Histopathological diagnosis of 50 colposcopy positive cases 13 were diagnosed as cervical carcinoma among these 12 (92.30%) were positive for OncoE6 cervical test. Without early screening of cervical precancerous and cancerous lesion it is not possible to reduce cervical cancer in developing countries like Bangladesh. Screening of women by a novel oncoE6 protein test helps in early detection. By early detection it will be potential to give suitable treatment in appropriate time so that competent to save economy, time and many lives.

Citation:

Abedin S. “Screening of Cervical Cancer Acts as New Insights” - For Early Detection and Prevention by a Modern OncoE6 Protein Detection Assay. Ann Short Reports. 2020; 3: 1055.

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