Ann Pregnancy Birth | Volume 1, Issue 1 | Research Article | Open Access

Preterm Premature Rupture of Membranes and Neonatal and Maternal Outcomes

Ilker Kahramanoglu1*, Olcay Ilhan2, Ozge Kahramanoglu2 and Fatma Ferda Verit2

1Department of Obstetrics and Gynecology, Istanbul University, Turkey
2Department of Obstetrics and Gynecology, Suleymaniye Maternity Research and Training Hospital,Turkey

*Correspondance to: Ilker Kahramanoglu 

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Objective: The management of Preterm Premature Rupture of Membranes (PPROM) remains controversial. PPROM may lead significant maternal and neonatal complications.
Methods: Retrospective data of PPROM cases managed in Suleymaniye Maternity Research and Training Hospital between 2008 and 2012 were collected and analyzed using SPSS.
Results: There were 192 women included in this analysis. Mean latency period was 5.7 ± 6.2 days. Latency period differed significantly according to gestational age. Less advanced gestational age, higher values of initial leucocyte and CRP and lower level of initial AFI were associated with an increased risk of chorioamnionitis. Prolongation of latency period increased the risk febrile morbidity. The most common neonatal morbidities were respiratory distress syndrome (n=88, 45.8%), hyperbilirubinemia (n=67, 34.8%), sepsis (n=33, 17.1%), and congenital pneumonia (n=18, 9.3%). Neonatal mortality rate was 6.7%.
Conclusion: Prediction and diagnosis of maternal and neonatal complications are crucial in women with PPROM. Randomized controlled trials are needed to enlighten the controversial issues regarding PPROM management.


PPROM; Preterm birth; Chorioamnionitis


Kahramanoglu I, Ilhan O, Kahramanoglu O, Verit FF. Preterm Premature Rupture of Membranes and Neonatal and Maternal Outcomes. Ann Pregnancy Birth. 2018; 1(1): 1002.

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