Ann Plast Reconstr Surg | Volume 7, Issue 3 | Research Article | Open Access
Yankai Z1*, Hui-Xin C2, Haibing C2, Tao W1, Zhimou W2, Jianfeng S2 and Yuedong C1
1Department of Urology, the First Affiliated Hospital of Xiamen University, China
2Department of Urology, Zhangzhou Hospital of Traditional Chinese Medicine Affiliated to Fujian University of Traditional Chinese Medicine, China
*Correspondance to: Zeng Yankai
Fulltext PDFObjective: To investigate the effect of allogeneic Human Acellular Dermal Matrix (HADM) in the treatment of penile hypospadias.
Methods: The data from January 2019 to December 2022 were compared 30 cases were treated with Tubularized Incised Plate urethroplasty (TIP), and 28 cases were treated with Tubularized Incised Plate urethroplasty (TIP) + HADM covering for newly treated children with penile hypospadias.
Results: There were 6 cases of mild urethral meatus retraction, 8 cases of urethrocutaneous fistula requiring reoperation, and 0 case of urethral stricture after the application of Tubularized incised Plate urethroplasty (TIP). After application of TIP and HADM, 6 cases of urethral meatus retraction, 2 case of urethrocutaneous fistula requiring reoperation, and 0 case of urethral stricture were observed. The incidence of urethrocutaneous fistula requiring reoperation was statistically significant (P<0.05), while There was no significant difference in the incidence of urethral meatus retraction and urethral stricture between the two groups (P>0.05).
Conclusion: Allogenic Human Acellular Dermal Matrix (HADM) as a "protective layer" of the new urethra can effectively reduce the incidence of urine leakage during the operation of penile hypospadias.
Hypospadias; Allogeneic human acellular dermal matrix; Tubularized incised Plate urethroplasty; Urethrocutaneous fistula
Yankai Z, Hui-Xin C, Haibing C, Tao W, Zhimou W, Jianfeng S, et al. Clinical Application of Allogeneic Human Acellular Dermal Matrix in the Treatment of Penile Hypospadias. Ann Plast Reconstr Surg. 2023; 7(3): 1112..