Ann Plast Reconstr Surg | Volume 1, Issue 1 | Case Report | Open Access

Dermatofibrosarcoma Protuberans: Trauma and Genetics

Stefanos Boukovalas¹, Alexander C Castillo¹, Danielle Andry¹, Nicholas Lombana², Suimin Qiu³ and Kevin DJ Murphy^1*

¹Division of Plastic Surgery, Department of Surgery University of Texas Medical Branch at Galveston, Texas, USA
²University of Texas Medical Branch School of Medicine, Texas, USA
³Department of Pathology University of Texas Medical Branch at Galveston, Texas, USA

^*Correspondance to: Kevin DJ Murphy 

Fulltext PDF

Abstract

Dermatofibrosarcoma Protuberans (DFSP) is a rare dermal sarcoma which can be misdiagnosed by non-specialists as a keloid, hypertrophic scar, sebaceous cyst or lipoma. It has high local recurrence rates but only metastasizes in 2% to 4% of cases. DFSP presents a challenge for the surgeon, as its delayed diagnosis allows more extensive radial and vertical growth than can be clinically appreciated. Extensive spread in the dermis results in a much larger defect requiring specialized reconstruction. DFSP has been linked with genetic deregulation; however, the literature repeatedly suggests an association with trauma, especially in young patients. We use one of our patients to illustrate a case of dermatofibrosarcoma protuberans of the right hip in a 24-year-old male with a history trauma to the same area 5 years prior to presentation. A thorough literature review is presented with diagnostic and treatment recommendations.

Keywords:

Dermatofibrosarcoma protuberans; Lower extremity and trunk sarcoma; History of trauma

Citation:

Boukovalas S, Castillo AC, Andry D, Lombana N, Qiu S, Murphy KDJ. Dermatofibrosarcoma Protuberans: Trauma and Genetics. Ann Plast Reconstr Surg. 2017;1(1):1001.