Ann Med Med Res | Volume 6, Issue 1 | Review Article | Open Access

Are We Ready? The Paradox of Nutritional Interventions for Gastrointestinal Cancer

Wang K¹, Zhang G¹ and Li Y^2*

¹Second Clinical Medical College, Zhejiang Chinese Medical University, China
²Department of General Practice, The Second Affiliated Hospital, Zhejiang Chinese Medical University, China

^*Correspondance to: Yanhua Li 

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Abstract

Increasingly literature has demonstrated the promising effects of dietary interventions as adjunctive anti-cancer treatment. However, the precise mechanisms of how diets influence cancer metabolism and the interactions in the tumor microenvironment are still not fully understood. Current studies are mainly focused on the experimental animal models, with conflicting and mixed results. Factors such as the different cancer types, hereditary features and the nutritional status of the host are all possible explanations. Herein, we gather the current evidence on several mainstream nutritional strategies in the treatment of gastrointestinal oncology, reviewing both benefits and risks, and hopefully contribute to the directions of future research.

Keywords:

Keywords: Dietary interventions; Cancer; Autophagy; Fasting; Oncology; Tumor microenvironment (TME); Glycolysis; Cachexia

Citation:

Wang K, Zhang G, Li Y. Are We Ready? The Paradox of Nutritional Interventions for Gastrointestinal Cancer. Ann Med Medical Res. 2023; 6: 1061..