Ann Med Med Res | Volume 3, Issue 1 | Research Article | Open Access

Evaluation of the Relationship between Insulin Resistance and Macronutrient Intake in Four Subgroups of Polycystic Ovary Syndrome (PCOS) based on Rotterdam Diagnostic Criteria

Maryam Movahedinezhad1, Saeide Ziaei1* and Anooshiravan Kazemnezhad2

1Department of Reproductive Health, Tarbiat Modares University, Iran
2Department of Biostatistics, Tarbiat Modares University, Iran

*Correspondance to: Saeide Ziaei 

Fulltext PDF


Introduction: Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. It is linked to genetic and environmental factors such as nutrition. Insulin resistance is one of the major pathological changes in PCOS. This study aimed to determine the relationship between insulin resistance and macronutrient intake in PCOS subgroups.
Methods: In vitro and clinical studies and completing 168-items PPQ Frequency Questionnaire were conducted for all macronutrients.
Results: There was a significant relationship between HOMA-IR and some dietary components (P<0.05). (Increased calorie in group A, increased total fat intake in group C, lower intake of unsaturated fats (PUFA and MUFA) in group D and higher intake of Saturated Fat (SFA) and protein intake in control group). There was no correlation in subgroup B (ovulatory phenotype).
Conclusion: Due to the significant relationship between insulin resistance and some dietary components in PCOS subtypes, it is recommended to maintain a balance in carbohydrate and fatty acids intake, increasing dietary fiber to improve health parameters in PCOS subjects.


Nutrition; Polycystic Ovary Syndrome; Insulin Resistance


Movahedinezhad M, Ziaei S, Kazemnezhad A. Evaluation of the Relationship between Insulin Resistance and Macronutrient ntake
in Four Subgroups of Polycystic Ovary Syndrome (PCOS) based on Rotterdam Diagnostic Criteria. Ann Med Medical Res. 2020; 3:1025..

Subscribe to Our Newsletter