Ann Infect Dis Epidemiol | Volume 2, Issue 1 | Review Article | Open Access

The Basic Knowledge of Varicella Zoster Virus (VZV) Molecular Genetic Testing

Vanda Boštíková¹, Radek Sleha^1*, Sylva Janovska¹, Miloslav Salavec², Roman Chlíbek¹, Miroslav Špliňo¹ and Pavel Boštík^1,3

¹Department of Military Health Sciences, University of Defence, Czech Republic,
²Department of Dermatology, Charles University Medical School and University Hospital, Czech Republic
³Department of Infectious Diseases, Charles University Medical School and University Hospital, Czech Republic

^*Correspondance to: Radek Sleha 

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Abstract

VZV is unique among the herpes viruses in its transmission by inhalation of aerosolized virus particles. Infection via the respiratory route increases the opportunity for rapid spread of the virus through susceptible populations and exposure of those already latently infected. The genotyping of VZV helps to better understand differences in properties of individual wild type and/or vaccine VZV strains; inform about pathogenic potential of individual VZV strains and help to detect mutations in functionally important gene and analyze their effects on phenotype.

Keywords:

Varicella-zoster virus; Herpes zoster; Molecular genetic; Genotyping

Citation:

Boštíková V, Sleha R, Janovska S, Salavec M, Chlíbek R, Špliňo M, et al. The Basic Knowledge of Varicella Zoster Virus (VZV) Molecular Genetic Testing. Ann Infect Dis Epidemiol. 2017;2(1):1008.