Ann Clin Toxicol | Volume 1, Issue 1 | Review Article | Open Access
Rhythm Rajesh Kumar and Barna Ganguly*
Department of Pharmacology, Pramukhswami Medical College, Karamsad, India
*Correspondance to: Barna Ganguly
Fulltext PDFAntihormonal treatment is currently the mainstay therapy in hormone receptor positive breast cancer patients after adjuvant chemotherapy or after surgical resection. However long term use of antihormonal therapy can lead to various side effects which may affect patient’s daily activities. This study was done to assess certain parameters on quality of life in day to day activities of the breast cancer patients who were on hormonal therapy based on recently published articles. This was an evidence based review of published studies on quality of life related to various side effects of hormonal therapy in breast cancer patients. Literature search was done based on English language, full text freely available journal articles indexed in PUBMED database over last 5 years. MeSH terms used for retrieving the articles were hormonal therapy, quality of life, breast cancer through Boolean method. Thirty articles were identified out of which seven articles were selected according to inclusion criteria and are discussed in this review. Data on the quality of life related to commonly reported side effects with different hormonal therapies were collected from these articles. Different scales were used by different authors in those published studies. The commonality of adverse events was found to be on musculoskeletal system, vasomotor symptoms and sexual function in these studies and is discussed in this review.
Hormonal therapy; Quality of life; Breast cancer
Kumar RR, Ganguly B. Quality of Life in Relation to Hormonal Therapy in Breast Cancer Patients- an Evidence Based Review. Ann Clin Toxicol. 2018; 1(1): 1005.