Bayanduuren B, Altankhuyag B, Enkhbayar D, Batbaatar G, Mishigdorj L, Bulgan CH,
Grand Med Hospital, Ulaanbaatar, MongoliaFulltext PDF
Introduction: Worldwide, the highest incidence rates (up to 7.5 per 100,000 in men and 23 per 100,000 in women) occur among populations in the Western part of South America (Chile and Peru), in North American Indians, in Mexican Americans, and in northern India. The best characterized risk factor for the development of gallbladder cancer is chronic inflammation associated with gallstones. Metastatic clear cell carcinoma in the gallbladder is extremely rare, with reported frequencies of less than 0.6% in large autopsy reviews. Case Presentation: Fifty four year old female, with no prior medical conditions presented with a 10 days history of upper abdominal pain. Last 4 days ago right abdomen upper quadrant pain, vomiting. Routine hematological leukocytosis and biochemical tests were CRP increased. An abdominal ultrasound revealed the gallbladder is enlargement, about 6.0 cm × 3.0 cm like the mudstone in the gallbladder. GB wall thickening/double. Common bile duct is dilated 1.2 cm. Computerized tomography imaging: Moderate thickening with surrounding mild edematous changes in wall of the gallbladder. Size of the GB is moderated dilated with diffuse sludges. IHBD is no dilated; CBD is mild dilated 1.2 cm and no sign of biliary tract obstruction. An open cholecystectomy, upon pathologic investigation, the morphologic and immunophenotypic features supported a diagnosis of clear cell variant of gallbladder carcinoma. Discussion: Gallbladder cancer was first described in 1777. Clear cell gallbladder carcinoma was first reported in 192. Clear cell carcinoma represents on average over 90% of all malignancies of the kidney. Approximately 20% to 30% of patients with clear cell carcinoma have metastatic disease at presentation and nearly 50% of patients with advanced disease die within 5 years of diagnosis. Conclusion: Clear cell carcinoma very rare disease. Our team diagnosed during surgery and histological analysis. As a result of the surgery patient was completely healed and discharged from hospital. After from hospital discharged, we sent to national cancer center.
Bayanduuren B, Altankhuyag B, Enkhbayar D, Batbaatar G, Mishigdorj L, Bulgan CH, et al. Gallbladder Clear Cell Carcinoma: A Case Report. Ann Clin Surg. 2020; 1(2): 1007.