Ann Clin Med Res | Volume 2, Issue 3 | Mini Review | Open Access

Alterations in Body Fluids- Blood (Plasma, Erythrocytes, Leucocytes), Edema Fluid and Saliva as Indicators of Nutritional Status

Agarwal KN*, Agarwal DK and Mishra OP

Department of Pediatrics, Institute Medical Sciences, Banaras Hindu University, Varanasi, India

*Correspondance to: Agarwal KN 

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Abstract

In blood plasma and erythrocyte FαAN (Free Alpha Amino Nitrogen) and non-essential: Essential amino acid ratios were neither definitive nor early indicators of hypoproteinemia. Erythrocytes showed significant increase in glutamic acid. Erythrocytes have a long survival time (around 100 days) therefore; may not represent the recent changes. The FαAN in leucocytes was reduced in hypoproteinemia. The leucocytes life span is 13 to 20 days, thus fall in FαAN may be the earliest change in blood for diagnosis of protein deficiency. The concentrations of protein, FαAN and non-essential and essential amino acids ratio distributions in plasma and edema fluid were similar in Protein Energy Malnutrition (PEM), nephrotic syndrome, cirrhosis and congestive heart failure, so no further study was done. The studies on saliva showed that decrease in ferritin level in PEM was a sensitive early indicator, protein also decreased. The salivary iron was increased two times of serum level in PEM, unrelated to iron deficiency anemia, and compared to serum levels in iron overload conditions.

Keywords:

Nutritional Status; PEM; FαAN; Nonessential: essential amino acid ratios; Plasma; Erythrocyte; Leucocyte; Hypoproteinemia; Edema fluid; Saliva; Ferritin

Citation:

Agarwal KN, Agarwal DK, Mishra OP. Alterations in Body Fluids- Blood (Plasma, Erythrocytes, Leucocytes), Edema Fluid and Saliva as Indicators of Nutritional Status. Ann Clin Med Res. 2021; 2(3): 1031..

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