Ann Clin Immunol MicroBiol | Volume 1, Issue 1 | Case Report | Open Access
Ger T Rijkers1,2*, Ciska Lindelauf1, Heleen van Velzen-Blad2, Thijs W Hoffman3 and Diana A van Kessel3,4
1Department of Sciences, University College Roosevelt, Netherlands
2Laboratory for Medical Microbiology and Immunology, St Antonius Hospital, Netherlands
3Department of Pulmonology St. Antonius Hospital, Netherlands
4Department of Heart and Lungs, University Medical Center Utrecht, Netherlands
*Correspondance to: Ger T Rijkers
Fulltext PDFA newborn child, who suffered from two episodes of bacterial meningitis, was found to have an absence of IgG. Loss of IgG via kidneys or intestines was excluded. Next the mother was investigated who turned out to be agammaglobulinemic. IgG levels were below 1 g/L while IgM and IgA were normal. Mother was subsequently treated with gammaglobulin substitution therapy. The child produces normal levels of IgG and has remained infection free.
Rijkers GT, Lindelauf C, van Velzen-Blad H, Hoffman TW, van Kessel DA. Adoration of the Magi: Agammaglobulinemia of the Mother, Clinically Expressed in her Child. Ann Clin Immunol Microbiol. 2018;1(1):1002.