Ann Chron Dise | Volume 2, Issue 1 | Review Article | Open Access

Neuromodulation in Psoriasis and Psoriatic Arthritis

Eric J Yang1,2,*, Kristen M Beck1 and John Koo1

1Department of Dermatology, University of California - San Francisco, San Francisco, USA
2Department of Dermatology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, USA

*Correspondance to: Eric Yang 

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Abstract

Psoriasis and psoriatic arthritis are debilitating chronic diseases that can significantly impair quality of life. A wide array of effective novel medications have become available with increased understanding of the immunology of these diseases, but the role of the nervous system in psoriasis and psoriatic arthritis remains largely uncharacterized. However, psoriasis is widely recognized by patients and physicians as a stress-responsive disease, and stress-alleviation maneuvers have been shown to decrease the severity of psoriasis. Recent studies have demonstrated that vagus nerve stimulation can decrease inflammation in rheumatoid arthritis, a disease closely linked to psoriasis and psoriatic arthritis. In this paper, we discuss these recent findings of the role of the nervous system in decreasing inflammation in rheumatoid arthritis. Additionally, we will provide an overview regarding the pathophysiology of psoriasis and psoriatic arthritis and discuss how neuromodulation could translate to the treatment of patients with psoriasis and psoriatic arthritis.

Citation:

Yang EJ, Beck KM, Koo J. Neuromodulation in Psoriasis and Psoriatic Arthritis. Ann Chron Dise. 2018; 2(1): 1003.

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