Ann Cardiovasc Surg | Volume 1, Issue 1 | Case Report | Open Access

Treatment of a Myocardial Infiltrating Mediastinal Diffuse Large B-cell Lymphoma: A Case Report

Hassane Abdallah^1,2*, Gabriel Fortin³, Hussam Achour², Pier-Alexandre Vasil¹ and Marianne Coutu¹

¹Cardiac Surgery Department, University of Sherbrooke, Quebec, Canada
²Prince Sultan Cardiac Center, Al Hasa, Al Hofuf, Saudi Arabia
³Internal Medicine Department, University of Sherbrooke, Quebec, Canada

^*Correspondance to: Hassane Abdallah 

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Abstract

Although primary cardiac lymphoma is rare and challenging to diagnose due to nonspecific symptoms, secondary infiltration is more common, usually from the adjacent lung, breast, esophagus or thymus. However, very few cases describing the treatment of a myocardial infiltrating lymphoma are found in the literature. We report the case of a 28-year-old immune competent woman who presented with rapidly progressing heart failure symptoms and ischemic changes on her electro cardiogram. Different modalities of cardiac imaging showed a large mass compressing and infiltrating the right side of her heart. A biopsy was done and revealed the diagnosis of a mediastinal B-cell lymphoma. She was treated accordingly with steroids and multi cycles of chemotherapy (R-EPOCH protocol), without any major adverse cardiac event. Although the risk of a myocardial rupture remains possible, we describe a case which demonstrates that a myocardial infiltrating lymphoma can safely be treated with standard chemotherapy regimens.

Keywords:

Diffuse large B-cell lymphoma; Mediastinal lymphoma; Myocardial infiltration; Heart rupture

Citation:

Abdallah H, Fortin G, Achour H, Vasil P-A, Coutu M. Treatment of a Myocardial Infiltrating Mediastinal Diffuse Large B-cell Lymphoma: A Case \ Report. Ann Cardiovasc Surg. 2018; 1(1): 1001.