Ann Cardiol Cardiovasc Med | Volume 7, Issue 1 | Case Report | Open Access
Ahmad B1*, Shaukat T1, Rehman W2,3 and Muneeb A2,3
1Department of Internal Medicine, King Edward Medical University, Pakistan 2Department of Internal Medicine, United Health Services Hospitals, Wilson Regional Medical Center, USA 3Department of Cardiology and Cardiovascular surgery, United Health Services Hospitals, Heart and Vascular Institute, Wilson Regional Medical Center, USA
*Correspondance to: Behrawar Ahmad
Fulltext PDFGPIIb/IIIa inhibitors (e.g., Tirofiban, abciximab, and eptifibatide) are associated with rapid onset thrombocytopenia, occurring within minutes to hours after exposure. This is an intriguing case of Tirofiban-induced thrombocytopenia with platelet count dropping from 254 × 103/uL at baseline to 4 × 103/uL in 12 h after initiation of Tirofiban infusion. The drug was immediately discontinued and platelet count recovered quickly and spontaneously, reaching the normal range within the following 24 h. This case of Tirofiban-induced thrombocytopenia emphasizes the importance of regular platelet count monitoring when administering GPIIb/IIIa inhibitors especially tirofiban and the importance of recognizing and promptly managing such complications in the hospital setting.
Thrombocytopenia; Platelet dysfunction; Antiplatelet therapy; GPIIb/IIIa inhibitors; Tirofiban
Ahmad B, Shaukat T, Rehman W, Muneeb A. Tirofiban Induced Severe Thrombocytopenia with Spontaneous Recovery. Ann Cardiol Cardiovasc Med. 2023; 6(1): 1051..