Ann Cardiol Cardiovasc Med | Volume 1, Issue 1 | Research Article | Open Access

Heart Transplantation in Iran, a Single Center 15 Years Registry Report, Early and Mid-term Outcomes and Survival Rate

Mehrdad Salehi1, Ali Reza Bakhshandeh1*, Mehrzad Rahmanian1, Neal Kraus2, Jamshid Mirzaei3, Kianoush Saberi4, Mahmood Alemohammad4, Roya Sattarzadeh5 and Anahita Tavoosi5

1Department of Cardiovascular Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
2Board Certified American Board of Internal Medicine. Attending Physician at Rocky Mountain Senior Care Golden, Colorado, USA
3Board Certified American Board of Internal Medicine. Attending Physician at Swedish Medical Center, Denver, Colorado, USA
4Department of Anesthesia, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran
5Department of Cardiology and Cardiovascular Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

*Correspondance to: Ali Reza Bakhshandeh 

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Abstract

Introduction: Heart transplantation was first performed in Iran in July 1993 in Shariati Hospital affiliated with Tehran University of Medical Sciences. Cardiac transplants in Iran are described as being among the most successful of the routine surgeries performed within major Iranian medical centers. This study was conducted to evaluate the outcomes of patients who underwent a heart transplant at Imam Khomeini Medical Center affiliated with Tehran University of Medical Sciences via examination of 1-month, 1-year, 3-year, and 5-year survival rates.
Methods: We analyzed data of 276 patients who underwent heart transplantation in two different periods, (000-2005 and 2006-2016). The 1,3and 5 years survival rate was analyzed to show the outcome and survival rate.
Results: Overall 1, 3 and 5-years survival rate in our center was 46.6±28.1%, 37.8±28.8%, and 28.5±25.8%respectively. Overall 1-year survival excluding 30 days hospital mortality was 96.7±3.3%. The 1,3 and 5 years survival in the first period were 14.5±2%, 14.5±2%, and 10.4±2% respectively however in the second period it raised to 64.9±10.6%, 57.8±18%, and 50.4±8.6% respectively. In first period overall 30 days mortality was 76.6%, although it declined to 29.6% in the second term. RV dysfunction and multiple organ failure in 38 (14.5%) patients were the most common cause of early death in our patients. CMV infection was detected in 76 (29%) patients which was the most common infection in our cases.
Conclusion: This study shows that overall 1, 3, and 5 years survival rates in our recipients are going to raise which is noteworthy despite vast variety of impediment in our course of progress.

Keywords:

Iran; Heart transplant; Treatment outcome; Survival rate; Graft rejection; Registries

Citation:

Salehi M, Bakhshandeh AR, Rahmanian M, Kraus N, Mirzaei J, Saberi K, et al. Heart Transplantation in Iran, a Single Center 15 Years Registry Report, Early and Mid-term Outcomes and Survival Rate. Ann Cardiol Cardiovasc Med. 2017;1(1):1003.

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