Ann Arthritis Clin Rheumatol | Volume 3, Issue 1 | Review Article | Open Access

Sarcopenia, Osteoporosis and Frailty a Triad Comes of Age

Sánchez A1*, Vidal M2, Vidal Neira LF2,3,4 and Messina OD5

1Center of Endocrinology, Argentina
2Diagnostic Center for Osteoporosis and Rheumatic Diseases (CEDOR), Peru
3Hospital Maria Auxiliadora, Peru
4International Osteoporosis Foundation (IOF), Switzerland
5Rheumatology Service, Argerich Hospital, Argentina

*Correspondance to: Sanchez A, 

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The epidemiology and the clinical characteristics of three entities that lead to dysmobility, falls and fractures (osteoporosis, sarcopenia, and frailty) are reviewed. Osteoporosis is a worldwide health problem causing bone fragility and fractures. Sarcopenia is an age-associated decline of skeletal muscle mass and function. Frailty results from the accumulation of age-related deficits in different physiological systems and is a clinical state that leads to greater risks of adverse health outcomes, such as falls, fractures, hospitalizations, loss of independence, and death. The three entities have a common denominator (aging), but they can be secondary to other diseases. There are patients presenting with all three pathologies, which should be properly identified by the treating physicians.


Osteoporosis; Sarcopenia; Frailty; Aging; Dysmobility


Sánchez A, Vidal M, Vidal Neira LF and Messina OD. Sarcopenia, Osteoporosis and Frailty a Triad Comes of Age. Ann Arthritis Clin Rheumatol. 2020; 3(1): 1017.

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