Am J Pharmacol | Volume 1, Issue 1 | Mini Review | Open Access

Graphene and Composite based Biomaterials in Cartilage Tissue Engineering Application

Srinivetha Pathmanapan and Suresh Kumar Ananda Sadagopan^*

Department of Biochemistry and Biotechnology Laboratory, Council of Scientific and Industrial Research (CSIR), India

^*Correspondance to: Suresh Kumar Ananda Sadagopan 

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Abstract

Absence of vascularization and poor cellularity has leads to the limited healing capacity of cartilage. Major traditional treatments for cartilage defects have limitations such as mismatching with repaired region and less integration with donor site. Tissue engineering has now attracted the attention of researchers for the treatment of critical joint defect and injury, reconstruction of cartilage tissue. A key component of engineering a biomaterial is the use of appropriate biocompatible and biomimetic scaffolds. There is no standard biomaterial available in the field of cartilage tissue regeneration and repair of the cartilage injury. Presently carbon based materials such as graphene oxide is being used as fillers in biomaterials for their excellent mechanical stability and their biocompatibility. In this present review we will summarize the development of Graphene oxide infused hybrid biomaterials in the field of cartilage tissue engineering.

Citation:

Pathmanapan S, Sadagopan SKA. Graphene and Composite based Biomaterials in Cartilage Tissue Engineering Application. Am J Pharmacol. 2018;1(1):1006.