Am J Otolaryngol Head Neck Surg | Volume 1, Issue 5 | Research Article | Open Access
Evren Erkul1*, Ismail Yilmaz2, Gizem Issin3, Atila Gungor4, Engin Cekin5 and Dilaver Demirel6
1Department of Otorhinolaryngology, University of Health Sciences, Gulhane Medical School, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
2Department of Pathology, University of Health Sciences, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
3Department of Pathology, Erzincan Mengücek Gazi Training and Research Hospital, Turkey
4Department of Otorhinolaryngology, Medical Park Goztepe Hospital, Istanbul, Turkey
5Department of Otorhinolaryngology, University of Health Sciences, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
6Department of Pathology, University of Health Sciences, University of Health Sciences, Gaziosmanpasa Taksim Training and Research Hospital, Istanbul, Turkey
*Correspondance to: Evren Erkul
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Aim: The aim of this study is to assess the histopathological sub typing of the pleomorphic adenoma of the parotid gland which were treated with superficial parotidectomy and analyze the relationship with the adverse morphologic characteristics.
Materials and Methods: Demographic features and Hematoxylin and Eosin stained histologic slides of 71 patients that were treated with superficial parotidectomy for pleomorphic adenoma of the parotid gland were reviewed retrospectively. Histological subtypes, capsular characteristics as; capsular penetration, capsular integrity, satellite tumors, the presence or absence of pseudopodia and size of the tumors were evaluated.
Results: In total of 71 patients, 54 patients whose features met the inclusion criteria were included into the study. Both the stroma-rich and classic types were observed significantly as more common histological subtypes (p:0.016). There was no statistically significant relationship between any histological subtype and capsular characteristics and any histological subtype and tumor size (p:0.474). We only found a significant association between satellite nodules and tumor size that were larger than 4 centimeter (p:0.017).
Conclusion: There was no significant association between any histological subtypes, capsular features and tumor size but only satellite nodules were often observed when tumor was larger than 2 centimeters.
Parotid gland; Pleomorphic adenoma; Histopathology; Recurrence
Erkul E, Yilmaz I, Issin G, Gungor A, Cekin E, Demirel D. Correlation of Histopathological Sub Typing and Adverse Morphological Features of Pleomorphic Adenoma of the Parotid Gland. Am J Otolaryngol Head Neck Surg. 2018;1(5):1022.