Neurol Case Rep | Volume 3, Issue 1 | Case Series | Open Access
Vera Montes*, Catia Carmona, Sandra Sousa and Fernando Pita
Department of Neurology, Cascais Hospital Dr. Jose de Almeida, Portugal
*Correspondance to: Vera Montes
Fulltext PDFStroke like Migraine Attack after Radiation Therapy (SMART) syndrome is a rare and late complication of brain radiotherapy. It is characterized by episodes, usually reversible, of headache associated with focal neurological deficits, with typical changes in brain magnetic resonance imaging. We report here two cases of SMART syndrome in long term survivors of high grade brain tumor. Our two patients suffered multiple episodes of attacks characterized by headache, aphasia, and weakness or sensory disturbance. In both patients, the course of disease was unfavorable, and eventually leads to severe and permanent neurological damage. Our present two cases allow us to broaden the clinical spectrum of SMART syndrome, demonstrating that it may be presented as a reversible and benign form to an eventually irreversible form with a severe course and permanent disability. Although extremely rare, SMART syndrome should always be considered in patients with headache, recurrent neurological deficits and a history of cranial irradiation.
Stroke-like migraine attack; Primary brain tumor; Radiotherapy; Headache
Montes V, Carmona C, Sousa S, Pita F. Stroke like Migraine Attack after Radiation Therapy - A Classical Reversible Syndrome with an Unusual Unfavorable Outcome. Neurol Case Rep. 2020;3(1):1015..