J Neurol Neurosurg Spine | Volume 3, Issue 1 | Research Article | Open Access

Efficacy of Treatment Modalities for Management of Third Nerve Palsy Induced by Posterior Communicating Artery Aneurysm: Reports of 12 Cases with Short Literature Review

Mohan Karki and Bing Zhao*

Department of Neurosurgery, The Second Affiliated Hospital of Anhui Medical University, Neurovascular Diseases Research Center, China

*Correspondance to: Bing Zhao 

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Abstract

Posterior Communicating Artery Aneurysms (PComAAs) may induce third nerve palsy. The aim of our study was to evaluate clinical outcomes of surgical clipping versus endovascular coiling. We retrospectively analyzed seven patients who underwent endovascular coiling and five patients who underwent surgical clipping who had PComAAs associated with Third Nerve Palsy (TNP) at our centre. The following parameters: age of patients, size of aneurysms, Subarachnoid Hemorrhage (SAH), degree of third nerve palsy, symptoms to surgery period, and follow up period were assessed. In this study, it was found that: 58.3% (7/12) patients had been treated by endovascular coiling while 41.7% (5/12) patients received surgical clipping. Complete improvement of third nerve palsy was achieved in all five patients (100%) undergoing surgical clipping while only four (57.1%) patients had a complete recovery and an incomplete improvement was seen in 42.8% patients in patients undergoing endovascular coiling. Moreover, complete recovery of TNP was 44.8% and incomplete recovery was 44.2% for cases undergoing endovascular coiling out of 174 cases whereas complete improvement was seen to be 76% and incomplete improvement was 19.2% in patients out of 182 cases that underwent surgical clipping. It was found that the early management of third nerve palsy, the degree and severity of third nerve palsy at the beginning of insult contributed towards the influence of nerve recovery. We conclude the patients that have undergone different procedures should be followed up and investigated for a longer time before saying which procedure is best and most effective.

Keywords:

Posterior communicating artery aneurysms; Third nerve palsy; Endovascular coiling; Surgical clipping; Digital subtraction angiography

Citation:

Karki M, Zhao B. Efficacy of Treatment Modalities for Management of Third Nerve Palsy Induced by Posterior Communicating Artery Aneurysm: Reports of 12 Cases with Short Literature Review. J Neurol Neurosurg Spine. 2018; 3(1): 1010.

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