J Dent Oral Biol | Volume 3, Issue 6 | Mini Review | Open Access
Minić Ivan* and PejÄić Ana
Department of Periodontology and Oral medicine, University of Nis, Serbia
*Correspondance to: Minic Ivan
Fulltext PDFStem cells are called non-differentiated cells in the human body that have the ability to differentiate into specialized cells with a new specialized function. Dental tissues have been investigated for many years as a potential source for stem cell isolation. Important criteria for dental tissue stem cells are: healthy pulp, intact blood flow, absence of infection, deep caries and other pathologies. The best source of stem cells are the teeth of young, healthy patients, whose stem cells have the greatest ability of proliferation, but stem cells from permanent teeth of middle-aged people can also be used in the same way. This is a great advantage in terms of the length of life and almost safe use in future regenerative therapy, especially when it is known that the best stem cells for therapy are their own, because in this way the risk of neuro-compatibility and tissue rejection is minimized. The stem cells of dental pulp have opened new perspectives in the therapeutic use of these cells not only in the regeneration of dentine, tissue of periodonium and bone-joint tissue of the craniofacial region, but also in the treatment of neuro-trauma, autoimmune diseases, myocardial infarction, muscular dystrophy and connective tissue damage.
Stem cells; Dental tissue; Regenerative dentistry
Ivan M, Ana P. Application of Stem Cells in Dentistry. J Dent Oral Biol. 2018; 3(6): 1148.