Int J Family Med Prim Care | Volume 2, Issue 4 | Research Article | Open Access
Abha Prasad and Mritunjay Kumar Azad
Department of Physiology, J.N.K.T. Medical College, Madhepura, Bihar, India
*Correspondance to: Mritunjay Kumar Azad
Fulltext PDFBackground: Polycystic Ovarian Syndrome (PCOS) is a chronic, diverse endocrine disease that affects mostly women of reproductive age. It is commonly associated with menstrual dysfunction, infertility, hirsutism, acne, and obesity, among other symptoms. Material and Methods: This descriptive cross-sectional study was conducted in Jannayak Karpoori Thakur Medical College and Hospital, Madhepura, Bihar from January 2021 to June 2021. A sample size of 90 women of age group 15 to 39 years were recruited for this study. Based on the BMI and the clinical diagnosis of PCOS, the study group was divided into three groups. Women who were diagnosed as PCOS with BMI>25 as Group I (n=30); Women who were diagnosed as PCOS with BMI<25 as Group II (n=30); and age-sex matched clinically normal healthy women with BMI<25 as Group III (controls, n=30). Results: The mean age ± standard deviation between groups results not significant as p value >0.05. In addition, the mean height, mean weight and mean BMI ± standard deviation was for group I, II & III respectively and results was highly significant as p value <0.001. Similar results were found for waist, hip and waist and hip ratio with p value <0.05. Similar results also seen for systolic & diastolic BP, heart rate & lipid profile respectively. Conclusion: Heart rate variability test in PCOS women indicate that there is a sympathovagal imbalance in the form of increased sympathetic activity and parasympathetic withdrawal. In obese women with PCOS, correlated with BMI and WHR, and increase in LFnu, LF/HF ratio a marker of sympathovagal imbalance playing a major role increasing the cardiovascular risks and other comorbidities. PCOS women also related with total cholesterol, low density lipoprotein, high density lipoprotein and triglyceride levels. In all groups they show significant relationship with p value <0.05. That indicates BMI>25 kg/m2 showing bad lipid profile than BMI<25 kg/m2 and to healthy controls.
PCOS; BMI; Lipid profile; Heart rate variability
Prasad A, Azad MK. A Study of Heart Rate Variability and Lipid Profile in Women with Polycystic Ovary Syndrome. Int J Fam Med Prim Care. 2021;2(4):1048.