Int J Family Med Prim Care | Volume 2, Issue 4 | Research Article | Open Access
Amrendra Kumar Singh1, Gagan Gunjan2* and Rajkamal Choudhary1
1Department of General Medicine, JLNMCH, Bhagalpur, Bihar, India 2Department of General Medicine, RIMS, Ranchi, Jharkhand, India
*Correspondance to: Gagan Gunjan
Fulltext PDFBackground: The World Health Organization named COVID-19 caused by SARS-CoV-2 a global pandemic on March 11th, 2020. CRP increased dramatically in severe COVID-19 individuals from the outset, which is a marker of lung damage and progression. This virus activates the immune system, releasing a significant number of cytokines, including IL-6. The goal of the study was to look at the relationship between biomarker levels and COVID-19 illness severity and how that correlated with outcome. Material and Methods: A Cross sectional prospective hospital-based study done over a period of 7 months, from November 2020 to May 2021 on 250 SARS-CoV-2 patients at Department of General Medicine, JLNMCH, Bhagalpur, Bihar. Results: Most common age group in present study having COID-19 cases were 41 to 50 years i.e., 69 (27.60%) & males were affected i.e., 154 (58.80%) in comparison to females i.e., 96 (41.20%). In relation to distribution of symptoms among patients in present study it was found that maximum patients presented with fever, cough & sore throat i.e., 221 (88.40%), 187 (74.80%) & 193 (77.20%). Most patients suffered from moderate COVID-19 i.e., 116 (46.40%) followed by severe form i.e., 87 (34.80%) respectively. In correlation between distributions of CRP, IL6 with severity of COVID-19 results found were statistically significant with p-value <0.001. Conclusion: Assessment of levels of various biomarkers helps in the immediate categorization of patients into risk groups following diagnosis, ensuring optimal resource allocation, especially in places where HRCT facilities are not readily available, based on the significant association with severity of lung involvement.
COVID-19; WHO; Diabetes; RT-PCR;Covid-19; Covid; Corona Virus; Coronavirus disease 2019
Singh AK, Gunjan G, Choudhary R. Elevated Plasma IL-6 and CRP Levels Association with Adverse Clinical Outcomes in SARS-CoV-2 Patients: A Prospective Observational Study. Int J Fam Med Prim Care. 2021; 2(4): 1047..