Marcoccia A1 *, Modesti M1 , Cianfrocca C1 , Porciello R2 , Labardi L3 , Pellegrino F4 , Coppola L4 and Monello A4
1 Medical Vascular and Autoimmunity Unit, Ospedale Sandro Pertini, Italy 2 Department of Dermatology, Ospedale Sandro Pertini, Italy 3 Department of Plastic Surgery, Ospedale Sandro Pertini, Italy 4 Departement of Anatomic Pathology, Ospedale Sandro Pertini, ItalyFulltext PDF
Although COVID-19-associated cutaneous manifestations have been increasingly reported, their exact incidence has yet to be estimated, their pathophysiological mechanisms are largely unknown, and the SARS-CoV-2 role in their pathogenesis is still debated. We describe the clinical and histopathological features of 2 Italian patients with different cutaneous presentations after COVID-19 infection, observed and followed at the P.O. Sandro Pertini ASL Roma2. Both patients had COVID-19 positive serological tests, negative RT-PCR test for COVID-19 virus, negative for other viral and bacterial agents tests suggesting that COVID-19 infection can give rise to cutaneous manifestations through mechanisms that are not known yet, even after the elimination of the virus by the organism. Skin lesions decreased and disappeared after systemic corticosteroid therapy suggesting an immune-mediated inflammatory reaction.
COVID-19; Cutaneous manifestations; Skin
Marcoccia A, Modesti M, Cianfrocca C, Porcello R, Labardi L, Pellegrino F, et al. Cutaneous Manifestations Associated with Post COVID-19 Infection: Report of Two Cases. Ann Clin Case Rep. 2021; 6: 1940..