Department of Physical Medicine and Rehabilitation, Celal Bayar University School of Medicine, TurkeyFulltext PDF
The aim of this study was to evaluate the skin and subcutaneous musculoskeletal involvement of hypothyroidism and myxedema due to a differential diagnosis of Pendred syndrome. She was operated on 2 June 2018 for epidural hematoma, induced head trauma. She was hospitalized in the intensive care unit for 3 weeks. He presented with less than fifty percent limitation of range of motion in both upper extremities after discharge. She had a history of pituitary insufficiency and congenital hearing loss. Patient was using Hydrocortisone 5 mg 3.1, levotrioxin 125 mcg 1.1, norgestrel-estradiol 2 mg 1.1 and hearing aid. Phenotypically, body mass index was low (15 kg/m2) and growth retardation was present. Endocrine consultation was requested for differential diagnosis of Pendred syndrome and the syndrome was excluded. Elbow, shoulder and right wrist joints were applied electrotherapy and stretching exercises. At the end of 1 month, full range of motion was achieved. In the lower extremity environment measurement for myxedema, 1 cm more diameter difference was measured in the left leg. Cutaneous-subcutaneous ultrasound revealed no signs of myxedema and the cutaneous and subcutaneous tissue were normal. Pendred syndrome; is a congenital condition that can make changes under the skin, hypothyroidism and myxedema. There is not enough information about cutaneous and subcutaneous involvement in hypothyroidism including Pendrend syndrome in the literature. Although there was not Pendred syndrome our case, hypotroidic and this issue was pointed out.
Unlu Z. Ultrasonographic Evaluation of Cutaneous and Subcutaneous Tissue in an Empty Sella. Ann Clin Case Rep. 2019; 4: 1630.