World J Oral Maxillofac Surg | Volume 2, Issue 3 | Research Article | Open Access
Lignou Sophia1 *, Maria Evangelia K1 and Sennis Panagiotis2
1Department of Dentistry, Athens Naval Hospital, Greece 2Department of Oral and Maxillofacial Surgery, Athens Naval Hospital, Greece
*Correspondance to: Lignou Sophia
Fulltext PDFThe removal of third molar teeth is one of the most frequently performed procedures in the OMFS outpatient clinic. The use of antibiotics in this procedure is a subject of conflict among the surgeons. Most clinicians use amoxicillin, metronidazole, amoxicillin with clavulanic acid, clindamycin, cephalosporin and other antibiotics, in order to prevent postoperative complications. The aims of this study were to determine current antibiotic prescribing patterns in our department, to compare the effectiveness of these three different antibiotics, cefuroxime, clindamycin and amoxicillin according to the postoperative symptoms of the patients, to find a correlation of antibiotic prophylaxis and difficulty of extraction with postoperative inflammatory complications and also to provide an evidence-based study on antibiotic prophylaxis for the extraction of third molars. A total of 120 extractions in 100 patients, 70 males and 30 females with impacted and semi-impacted third molars were enrolled in the study. They separated in 3 groups randomly according to the antibiotic they got. Cefuroxime 500 mg P.O. was administered to 41 patients, Clindamycin 300 mg P.O. to 33 patients and Amoxicillin 500 mg P.O. to 26 patients. Antibiotics have been administered for 7 days. All surgical extractions were carried out by the same surgeons. The postoperative complications/clinical parameters which were examined on 7 and 15 days were swelling, pain, trismus, surgical wound dehiscence, pus extrusion and dry socket. The difficulty of extraction, especially in case of ostectomy, was significantly associated with the postoperative complications. In conclusion, there are no statistically significant differences between the three groups of patients.
Dental; Implants; Antibiotics; Amoxicillin; Cefuroxime; Clindamycin; Third molars; Surgical extraction
Sophia L, Maria Evangelia K, Panagiotis S. Antibiotics in the Surgical Extraction of Third Molars: A Comparative Study. World J Oral Maxillofac Surg. 2019; 2(3): 1029.