World J Breast Cancer Res | Volume 1, Issue 1 | Research Article | Open Access

Feasibility of Permanent Breast 103Pd Seed Implant forEarly Stage Breast Cancer

Jeremy Colliaux*, Eric Vigneault, Nicolas Varfalvy and Anne Dagnault

Department of Radiation Oncology, CHU de Quebec-Laval University, Canada

*Correspondance to: wjbcr-v1-id1004 

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Abstract

Background and
Purpose: In order to improve the offer of care in our institution, the goal of this study was to evaluate the logistical feasibility of Permanent Breast Seed Implant (PBSI) with 103Pd in women with early stage breast cancer. Material and
Methods: From June 2014 to January 2016 eligibility criteria for PBSI were evaluated for all patients seen for breast cancer treatment after breast conserving surgery. After patient consent and acquisition of Ultra Sound (US) imaging, some patients were excluded based on the following morphological criteria: smaller breast, larger seroma, closer the skin or the chest wall.
Results: Among the 1,032 patients seen in consultation, 184 (17.8%) were eligible according to clinical and histological criteria. Ineligibility was mostly due to chemotherapy, tumor size, surgical margin, positive lymph node and multifocal disease. Of those patients, 100 were not informed of the study for various reasons: logistical issues such as technical availability, not enough consultation time, waiting for chemotherapy decision, uncertain diagnosis or oversight (45%), breast clinical morphology (18%), no radiation therapy (17%) and psychological disorders (14%). Among the 24 patients interested in PBSI, 19 were finally excluded after breast US imaging due to the seroma cavity dimension, the proximity of the chest wall or that of the skin surface.
Conclusion: The recruitment in the study was lower than expected mainly for logistical issues. We hope that our good preliminary results will convince our colleagues to present the technique to eligible patients in order to increase recruitment. This study shows the difficulty to introduce a new technique in a busy department.

Keywords:

Brachytherapy; Breast cancer; Permanent seed implant; Feasibility; Logistic

Citation:

Colliaux J, Vigneault E, Varfalvy N, Dagnault A. Feasibility of Permanent Breast 103Pd Seed Implant for Early Stage Breast Cancer. World J Breast Cancer Res. 2018;1(1):1004.

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