Oncol Case Rep J | Volume 3, Issue 3 | Case Report | Open Access
Sylwia Szklarzewska1* and Aurélien Simon2
1Department of Geriatrics, Université Libre de Bruxelles, Belgium
2Department of Oncology, Centre Hospitalier Epicura, Belgium
*Correspondance to: Sylwia Szklarzewska
Fulltext PDFWe report a case of a 74 year-old female presenting a picture of intestinal sub-occlusion with major weight loss. An abdominal mass was detected on physical exam. A uterine origin of the mass was suspected, based on the abdominal MRI. The histology and the immunochemistry confirmed the diagnosis of PEComa. The laparotomy let to discover a vascular mass adhering to the mesentery, the small intestine and to the transverse colon. The mass has been entirely resected. The patient presented a paraneoplastic eosinophilia. The patient has left the hospital after 3 weeks and gained 6 kg.
PEComa constitute a rare family of Mesenchymal tumors expressing both melanocytic and myoid immunomarkers.
Most of the cases benefit exclusively from a surgery and show no recurrence thereafter.
For metastatic disease, a variety of chemotherapy regimens has been described and appears to bring some favorable results. There are some encouraging data showing the advantage of targeted therapies, especially with mTOR inhibitors. A paraneoplastic hypereosinophilia hasn’t been mentioned in any former PEComa related articles.
We report a rare case of PEComa, which could be treated by surgery when the patient was considered as palliative situation.
PEComa; Eosinophilia; Hypereosinophilia
Szklarzewska S, Simon A. A Rare Cause of Bowel Obstruction with Hypereosinophilia - Case Report and Literature Review. Oncol Case Report J. 2020;3(3):1028..