Oncol Case Rep J | Volume 3, Issue 2 | Case Report | Open Access

Primary Conjunctival Follicular Lymphoma: A Case Report and Literature Review

Ruby Maini1*, Manjari R Regmi1, Nitin Tandan1, Priyanka Parajuli1, Odalys Lara Garcia1, Fawwad Zaidi1,2 and Aziz Khan1,2

1Department of Internal Medicine, Southern Illinois University School of Medicine, USA
2Department of Hematology-Oncology, Southern Illinois University School of Medicine, USA

*Correspondance to: Ruby Maini 

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Background: Extranodal non-Hodgkin lymphoma accounts for approximately 20% to 30% of reported cases of lymphoma. Of these, roughly 8% occur within the orbit with a smaller portion occurring within the conjunctiva. Ocular manifestations of conjunctival lymphoma are quite variable and can mimic common ocular pathologies, thus requiring a high degree of suspicion for diagnosis.
Case Presentation: A 68-year-old male patient with a history of papillary urothelial cancer who underwent transurethral resection of the prostate in 2014 presented to the outpatient clinic for left neck swelling. On examination, the heath care provider incidentally noted right medial cantus swelling of the right eye. Computed tomography of the neck revealed Warthin’s tumor which required surgical excision. Magnetic resonance imaging of the orbits revealed an asymmetric thickening of the right lacrimal caruncle (13 mm). On biopsy, the diagnosis of follicular (non-Hodgkin lymphoma) of the conjunctiva was made.
Conclusion: A literature review was performed in order to investigate unique presentations and management approaches for primary conjunctival lymphoma. This report highlights the various manifestations of conjunctival follicular lymphoma, the difficulties of diagnosis, and unique management strategies.


Non-Hodgkin lymphoma; Ocular adnexal lymphoma; Conjunctival lymphoma


Maini R, Regmi MR, Tandan N, Parajuli P, Garcia OL, Zaidi F, et al. Primary Conjunctival Follicular Lymphoma: A Case Report and Literature Review. Oncol Case Report J. 2020;3(2):1021..

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