Joey Elkhoury1,2, Maher Abdessater1,2*, Anthony Kanbar1,2, Halim AKL1,2, Charbel El Hachem1,2, Rami Halabi1,2, Leony Antoun1,2, Fadi NASR1,2, Johnny Boustany1,2 and Raghid El Khoury1,2
1Department of Oncology, Notre Dame Des Secours University Medical Center, Lebanon
2Department of Oncology, Holy Spirit University of Kaslik, Lebanon
Background: Adenocarcinoma of the prostate is often considered an elderly disease, which shifts the attention from early-onset prostate cancer, affecting those who are younger than 55 years of age. We will be reporting a case of young age metastatic adenocarcinoma of the prostate to shed light on the importance of an early diagnosis and subsequent prognosis.
Case Presentation: A previously healthy 36-year-old policeman presented with lower urinary tract symptoms, especially afebrile dysuria for a few weeks upon clinical presentation, worsening in the next few months. On admission, prostate specific antigen was elevated at 7000 ug/nL and a pelvic MRI revealed a tumoral process infiltrating the entire prostate gland and its capsule, invading the left seminal vesicle and bladder floor, reaching the rectum, with bilateral pelvic adenopathies, and secondary bone lesions. The patient was found to have a positive BRCA1 gene. Conclusion: The incidence of early-onset prostate cancer is increasing and should be considered as a real threat to young men. It should be differentiated from its late-onset counterpart, being more aggressive if diagnosed at an advanced stage. A clear, effective and adequate screening strategy tailored for early-onset advanced prostate cancer is an interesting subject of research for the years to come.
Early-onset prostate cancer; Young male; Screening strategy; PSA; PLAP
Elkhoury J, Abdessater M, Kanbar A, Halim AKL, El Hachem C, Halabi R, et al. Metastatic Adenocarcinoma of Prostate in a 36-Year-Old Mediterranean Man. Oncol Case Report J. 2020;3(1):1016..